Mesenchymal stem cells: immune evasive, not immune privileged
نویسندگان
چکیده
منابع مشابه
Mesenchymal Stem Cells: Interactions with Immune Cells and Immunosuppressive-Immunomodulatory Properties
Abstract Background and Objectives Recently, mesenchymal stem cells have attracted much attention in regenerative medicine and cell-based therapies. Mesenchymal stem cells are used in regenerative medicine mainly based on their capacity to differentiate into several cell lineages, low immunogenicity, and in particular their anti-inflammatory and immunosuppressive-immunomodulatory properties. ...
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Sertoli Cells (SCs) in the testes have evolved to possess unique immune privileged properties to protect the developing germ cells from immunological attack. These immune privileged properties are not restricted to the testis, as SCs survive when transplanted across immunological barriers as alloand xeno-grafts. Here we discuss the therapeutic potential of transplanted SCs in protecting cells, ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2014
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt.2816